I have an IUD (Mirena), this is my second one. It is due to come out next year. I was wondering what the correlation is between the IUD and depression? I have a history of depression, but it has gotten worse. I’m currently on 3 different antidepressants, which really are not helping.

When I think about it now, it seems to have increased since the time I had the second one placed 4 years ago. I know hormones can have an impact on mood/mental well-being. Do you think there is a connection between the two?

Dr. Holly L. Thacker explains what perimenopause is and when women are in perimenopause. She explains classic symptoms and signs you are entering perimenopause and making the transition to menopause.

Dr. Holly L. Thacker explains skin and hair changes during menopause. The culprit for the post-menopausal changes in your hair and skin is the lower levels of the hormone estrogen circulating in your body. Loss of estrogen makes your skin thinner and more delicate, and can cause your hair to thin out. Watch for helpful tips.

Color equals nutrition and this salad is overflowing with flavor, color and garden fresh favorites. This Great Garden Salad recipe is from Holly Clegg's trim&TERRIFIC EATING WELL TO FIGHT ARTHRITIS: 200 easy recipes and practical tips to help REDUCE INFLAMMATION and EASE SYMPTOMS.

Read guest columnist Stetson T. Thacker, PhD’s column to understand why you want and need brown fat and how to develop more brown fat!

Dianne Dunkelman, founder of the National Speaking of Women’s Health Foundation, has been named the new Chief Strategist of Speaking of Women’s Health.

I am 66 years old and have osteoporosis. My primary care doctor suggested Reclast, but my gynecologist suggested Prolia. I have never been treated before for osteoporosis. I also have had a portion of my thyroid removed 7 months ago.

I have two questions:

1. Are these two drugs the same?
2. How will treatment affect my thyroid?

Download our comprehensive treatment guide to learn more about the newest and latest treatment options available for urological congenitalism.

Download our free guide to learn more about treatment options for all stages of testicular cancer, information on fertility options before and after treatment and online medical second opinion services.

Download our comprehensive treatment guide to learn more about the risks of chronic high blood pressure, what causes resistant hypertension and treatment options for resistant hypertension.

To help you decide if sperm banking is right for you, download our free guide to learn more about the sperm banking process and a list of available tests for fertility.

Read guest columnist Dr. Heather Hirsch's column on overuse injuries and how these injuries can be prevented.

I have been using Intensity for approximately two months with no problems. I have been experiencing uncomfortable vaginal itching the last couple of days. I did not use the Intensity today.

I do have e-string and was using Premarin, but I have not used those for the last couple of weeks. I would appreciate any advice you could provide me to help relieve my symptoms and how to proceed with the Intensity treatment.

I’m 48 and going thru menopause. I have gained 30 pounds and I am anemic. I take vitamins and iron pills, but I still have no energy or weight loss. I have two young kids and it’s hard to keep up with them. I need help with weight issues. I tried exercise and eating well, but nothing helps.

I’m 66 and I was on Hormone Replacement Therapy (HRT) for about 10 years, but stopped using it for the last seven years. Is there any evidence to show that I need to go back on HRT? If so, how long are you supposed to use HRT?

A best ever luscious cookie cake, picture perfect and perfect tasting from Holly Clegg's trim&TERRIFIC Too Hot in the Kitchen: Secrets to Sizzle at Any Age - 200 Simple and Sassy Recipes.

Cervical cancer, which still kills about 4,000 American women every year, is almost entirely preventable. Proper screening can catch early warning signs that could lead to cancer without the right treatment. But how often women should get screened and which tests should be used has been hotly debated by women, doctors and medical researchers for the past decade.On Thursday, the American College of Physicians weighed in with guidelines, endorsed by the American College of Obstetricians and…

I am experiencing numbness in my feet and tingling occasionally in my hands. My glucose is between 80 and 90. I used to be hyphypoglycemic and I wonder if I should have that checked?

Host Michael Krychman, MD

Bladder leakage is one of many health-related issues that our female patients deal with. There are newly available treatment options, including non-surgical options, to help remedy the problem. Host Dr. Michael Krychman welcomes Dr. Holly Thacker to decipher the pros and cons of the various options available. Dr. Holly L. Thacker, nationally known for her leadership in women’s health, is the founder of the Cleveland Clinic Women’s Health Fellowship and is currently Professor and Director of the Center for Specialized Women’s Health at Cleveland Clinic and Lerner College of Medicine at Case Western Reserve University. She is also author of two books: Women’s Health: Your Body, Your Hormones, Your Choices and Cleveland Clinic Guide to Menopause.

I just had a double mastectomy for stage 2 ductal cancer. It was hormone receptor positive. They told me I could not continue my Prempro, which I was using for hot flashes and insomnia. Since then, I have started Arimidex and have been in misery. My physician said I could consider stopping Arimidex if I wanted to restart hormone therapy because I feel so miserable. I would appreciate your thoughts and opinion on this matter. Thank you.