I am 66 years old and have osteoporosis. My primary care doctor suggested Reclast, but my gynecologist suggested Prolia. I have never been treated before for osteoporosis. I also have had a portion of my thyroid removed 7 months ago.

I have two questions:

  1. Are these two drugs the same?
  2. How will treatment affect my thyroid?


Reclast and Prolia are both osteoporosis medications classified as “anti-resorptives.” This means that they treat osteoporosis by decreasing bone turnover. You would not take both medications at the same time.

Thyroid disease may increase your risk for osteoporosis. Specifically, hyperthyroidism, or an overactive thyroid, can increase bone breakdown. If you have had your thyroid removed and are now on thyroid replacement, it is important that you get your thyroid levels checked at least annually to ensure that you are getting adequately replaced.

Having too much thyroid hormone can increase your risk for osteoporosis and fracture. However, treatment of your osteoporosis with Reclast or Prolia should not directly affect your thyroid disease. Please consult your endocrinologist prior to starting medications to ensure your safety.

All my best,
Speaking of Women’s Health nurse

June 3, 2015 at 2:40pm