Recently, I had a total knee replacement. After 3 months of Physical Therapy I am back at work, doing well for the most part.

On occasion, I have a large amount of swelling in the ankle of the same leg I had the knee replacement. This happens 2-3 times a week and not with any particular irritant. The swelling is enough to stretch my shoe out. I’d like to know if this is normal after this type of surgery?

I take several types of vitamins every day. Should I take them all at once or should I spread them out throughout the day?

I have an IUD (Mirena), this is my second one. It is due to come out next year. I was wondering what the correlation is between the IUD and depression? I have a history of depression, but it has gotten worse. I’m currently on 3 different antidepressants, which really are not helping.

When I think about it now, it seems to have increased since the time I had the second one placed 4 years ago. I know hormones can have an impact on mood/mental well-being. Do you think there is a connection between the two?

I am 66 years old and have osteoporosis. My primary care doctor suggested Reclast, but my gynecologist suggested Prolia. I have never been treated before for osteoporosis. I also have had a portion of my thyroid removed 7 months ago.

I have two questions:

1. Are these two drugs the same?
2. How will treatment affect my thyroid?

I have been using Intensity for approximately two months with no problems. I have been experiencing uncomfortable vaginal itching the last couple of days. I did not use the Intensity today.

I do have e-string and was using Premarin, but I have not used those for the last couple of weeks. I would appreciate any advice you could provide me to help relieve my symptoms and how to proceed with the Intensity treatment.

I’m 48 and going thru menopause. I have gained 30 pounds and I am anemic. I take vitamins and iron pills, but I still have no energy or weight loss. I have two young kids and it’s hard to keep up with them. I need help with weight issues. I tried exercise and eating well, but nothing helps.

I’m 66 and I was on Hormone Replacement Therapy (HRT) for about 10 years, but stopped using it for the last seven years. Is there any evidence to show that I need to go back on HRT? If so, how long are you supposed to use HRT?

I am experiencing numbness in my feet and tingling occasionally in my hands. My glucose is between 80 and 90. I used to be hyphypoglycemic and I wonder if I should have that checked?

I just had a double mastectomy for stage 2 ductal cancer. It was hormone receptor positive. They told me I could not continue my Prempro, which I was using for hot flashes and insomnia. Since then, I have started Arimidex and have been in misery. My physician said I could consider stopping Arimidex if I wanted to restart hormone therapy because I feel so miserable. I would appreciate your thoughts and opinion on this matter. Thank you.

I have been widowed for a long time and have met someone. Intercourse is extremely painful and I would like to get some easing of these symptoms. I’m 67.