Ask the Nurse

Is there a relationship between Myasthenia Gravis (MG) and menopause? Since I have MG should I take menopausal hormone therapy as suggested by my physician?


Autoimmune conditions, including Myasthenia Gravis (MG) and Systemic Lupus Erythematosus (SLE) have been associated with premature ovarian insufficiency (menopause before age 40) and early menopause (menopause between age 40-45). This occurs because the body’s immune system can attack the ovaries causing them to stop working earlier than the average age of natural menopause.

It is recommended that women with premature ovarian insufficiency or symptoms of natural menopause talk to a Menopause Specialist about hormone replacement therapy/hormone therapy and undergo additional evaluation if needed. Women with neurological conditions like MG, Multiple Sclerosis and Parkinson’s disease, may do better with estrogen if they are low in estrogen as estrogen helps support neurons, muscle and bone health.

All My Best,
Speaking of Women’s Health Nurse

January 22, 2019 at 10:42am