Understanding Peripheral Neuropathy and How To Manage It
January 14, 2026 • Season 4: Episode 2
Tingling toes. A strange electric buzz that won’t let you sleep. We sat down with Dr. John Morren, Director of the Neuromuscular Center at Cleveland Clinic, to unpack what truly drives peripheral neuropathy, how to read the early signs, and which treatments actually help you function and rest again.
We trace the most common causes—diabetes and the broader metabolic syndrome—while surfacing underrecognized risks like rapid weight loss, malabsorption after bariatric surgery, chemotherapy, infections, alcohol, and hidden vitamin pitfalls. B12 deficiency takes center stage as a treatable driver; we talk real thresholds, why neurologists aim above 400, and how methylmalonic acid exposes low B12 even when standard labs look “normal.”
Looking ahead, we explore AI as augmented intelligence: tools that flag high-risk patients in primary care, prompt simple screening steps, and sharpen EMG and nerve conduction studies to detect nerve damage earlier. It’s not man versus machine; it’s smarter care through synergy, personalizing treatment and expanding access without losing the human touch.
