Ask the Nurse

I am scared to use Vagifem for atrophy. My understanding was it would not penetrate into the uterus and was the lowest dose available, is that correct? If I use it for three months and feel better, can I go off it cold turkey?


Yes, Vagifem 10 ug inserted into the lower 1/3 of the vagina twice a week is the lowest does of vaginal estrogen and is very effective.

If you do not want to use vaginal estrogen, there is a non-estrogen oral medication called Osphena 60 mg that can be taken daily with breakfast.

Once you have lost estrogen, the vagina gets affected and if you stop effective therapy your symptoms and condition will recur.

All my best,
Speaking of Woman’s Health nurse

August 18, 2016 at 3:00pm