Ask The Nurse

To personally discuss a medical issue or to make an appointment, call 216-444-4HER (216-444-4437). You can also make an appointment at Cleveland Clinic. For your security, please do not use this form to email personal, confidential health information. We cannot diagnose or treat by email. Our email policies are explained further in this disclaimer. You may also wish to review our privacy statement. Disclaimer | Privacy

I am 49 years old and had a total hysterectomy three years ago. I use EstroGel (one pump daily on one arm). Is this a safe treatment and how long should I continue it? I tried stopping several months ago and experienced some pretty extreme mood swings, so I started using it again. I would really appreciate some advice. Thank you.

EstroGel is a bioidentical hormone which means it is derived from plant sources and altered to be similar to your body’s own estrogen.

If you’ve had a hysterectomy, estrogen only therapy is sufficient. Many studies address the benefits and risks of hormone therapy. The Women’s Health Initiative showed that women on estrogen alone who are your age (less than 60 years) and less than 10 years since menopause therapy decreased their rate of hip fracture and colon cancer and had no increased risk of stroke or breast cancer or heart disease.

Research on discontinuing hormone therapy is scant. Approximately 30% to 40% of people who stop (either by tapering doses or stopping "cold turkey") resume hormone therapy (HT). Studies have shown that women who have moderate to severe hot flashes experience most symptoms after stopping and are more likely to resume HT.

February 6, 2012 at 10:53pm

Share this article


Go back to the question archive